Herpes simplex virus type 1/adeno-associated virus hybrid vectors
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چکیده
منابع مشابه
Herpes Simplex Virus Type 1/Adeno-Associated Virus Hybrid Vectors
Herpes simplex virus type 1 (HSV-1)-based amplicon vectors have a large transgene capacity and can efficiently infect many different cell types. One disadvantage of HSV-1 vectors is their instability of transgene expression. By contrast, vectors based on adeno-associated virus (AAV) can either persist in an episomal form or integrate into the host cell genome, thereby supporting long-term gene ...
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ژورنال
عنوان ژورنال: Gene Therapy and Regulation
سال: 2003
ISSN: 1568-5586,1388-9532
DOI: 10.1163/156855803762295404